Posts Tagged ‘vaccines’

New Japanese Encephalitis Vaccine Reduces Side Effects

Wednesday, May 19th, 2010 by Guest Author

Good news for travelers throughout Asia.  There is a new vaccine against Japanese encephalitis that significantly reduces typical side effects.

We all know that mosquitoes transmit some very serious viruses to humans. In addition to malaria and dengue fever, another mosquito-driven disease is Japanese encephalitis virus (JEV).  As reported by the World Health Organization (WHO) JEV is endemic in parts of China, India, the Republic of Korea, Japan, the Russian Federation, islands in the Torres Strait of Australia, Nepal, Thailand, Viet Nam, Cambodia, the Lao People’s Democratic Republic, the Philippines, Taiwan, Indonesia, Malaysia, and Sri Lanka. Its breakouts are generally most prevalent during the summer and fall.

There is no treatment available for this disease which can lead to permanent damage to the nervous system or death. Though many vacationers or expats will not find themselves in high-risk areas during peak times, it is recommended by the Centers for Disease Control (CDC) that anyone travelling to an endemic area during a possible transmission season or those who are headed toward a potentially dangerous area should be vaccinated for JEV.

Historically, the vaccine was toxic to some people — especially those with a history of allergy to wasp/bee stings.  Many doctors were hesitant to give the traditional vaccine and if they did, they would advise recipients to stay in a country with decent medical facilities in case they were one of the rare cases to develop an allergic reaction within 10 days of receiving the vaccine.  Fortunately for those over 18 years of age, there is now a new vaccine that does not cause those side-effects and can be given as safely as any of our other vaccines.

In summary: If you are over 18 years old and travelling to one of the high risk areas mentioned above, ask your doctor for the new non-allergic Japanese encephalitis vaccine.

Author: Charlie Easmon, MBBS
Charlie Easmon, MBBS is a General Practitioner whose practice has a strong focus on Travel Medicine.  He is a Regional Physician Advisor for HTH Worldwide and the Medical Director for The Number One Health Group on Harley Street in London and ALC Global Health Insurance.  He is a member of the Royal College of Physicians, UK and has a Diploma in Tropical Medicine and Hygiene from the University of Liverpool.   Dr. Easmon is an Honorary Lecturer at the London School of Hygiene and Tropical Medicine. 

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H1N1 Flu: What We’ve Learned So Far

Tuesday, May 5th, 2009 by Frank Gillingham, MD

h1n1strain

As the evidence mounts that the H1N1 virus is beginning to stall out at as a “near pandemic” (currently WHO Level 5), what have we learned so far? First, although intense media coverage has sparked the sales of face masks and engendered a great deal of anxiety, CDC and WHO officials and the federal government have managed the outbreak with steady hands and cool heads (VP Biden excepted), resisting calls for borders to be closed; Containment is not feasible in a world so tightly knit by trade and travel patterns. As a prime example of how interdependent we have become, the New York Times noted that the base ingredient for the antiviral drug Tamiflu, shikimic acid, is manufactured mainly in China. Sealing our borders could leave us defenseless against H1N1.

Second, geneticists, who are sequencing H1N1 and posting the results on the Internet are beginning to conclude that the virus in its current form spreads barely well enough to keep itself going.  The transmissibility appears to be no speedier than ordinary flu which kills 36,000 annually in the U.S. and an estimated 250,000 – 500,000 worldwide.

Third, the story is not over. H1N1 may yet adapt to people in a dangerous way, which means that next winter we may be in for an unpleasant surprise. The virus, which so far has resulted mostly in mild illness, may have a much more devastating effect next flu season, which runs each year from November until March.  The good news is that scientists should have ample time to create a vaccine for this new H1N1 strain before next October, as vaccines typically take 3-4 months to develop.  It is likely that the WHO will recommend inoculation concurrent with the annual flu vaccination.

While we watch and wait, we should recognize that the term “pandemic” only describes how widely an infectious agent is distributed, not how severely it affects the population.  Unless we see a dramatic change in the next few days, it looks as though the current H1N1 virus will be manageable, at least for the next few months, as it takes up residence in the realm of human antagonists.

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Outbreak in Africa’s Meningitis Belt Means Travelers Need Immunization

Friday, April 24th, 2009 by Frank Gillingham, MD

High season is nearing the end in the annual battle against meningitis in many countries of equatorial Africa. According to the Centers for Disease Control , there have been over 25,000 suspected cases so far this year in an area that stretches from Mali and Senegal in the west to Ethiopia and Eritrea in the east. Nigeria and Niger have been especially hard hit. The high season for infections runs from December through June.

If you aren’t immunized, it isn’t safe to visit these countries at this time.

Forgive me this pause for a little education – Meningitis is an inflammation of the meninges – the thin lining of the brain and spinal cord. Symptoms may include severe headache, a stiff neck, fever, vomiting, a marked sensitivity to light, and delirium.  It is most commonly caused by the Neisseria meningiditis bacteria. Despite early and adequate treatment, 5-10% of patients die, usually within 24-36 hours.  Those who recover may experience brain damage, with hearing loss and/or learning disabilities in 10-20% of survivors.  The infection is spread by breathing in the small droplets of fluid from the sneezing or coughing of those affected. In short, it spreads quickly and it’s devastating.

http://gamapserver.who.int/mapLibrary/Files/Maps/Global_MeningitTravelers to the so called “meningitis belt” MUST be immunized.  Fortunately, the two commercial vaccines available in the United States (MPSV4 or Menomune and MCV4 or MenactraT) provide protection against the most common types of infection.  Students who are immunized against meningitis in preparation for dormitory living in the U.S.  typically receive these vaccines, but they should check with their physician to make sure they are protected.  Those traveling through  or living in the meningitis belt should adopt strategies for avoiding the illness such as staying away from large gatherings, refraining from sharing drinking and eating utensils, and seeking medical attention at the first sign of a headache, fever, stiff neck, or purplish rash. 

The CDC has a website for frequently asked questions about meningitis and the World Health Organization provides useful information on its website.  Though there is no guarantee that vaccinations will eliminate your chance of contracting the infection, they are safe, effective and highly recommended.

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